Medicine : Cyclomune 0.1(5ml)

Name:Cyclomune 0.1(5ml)
Manufacturer:Sun Pharmaceutical Industries Ltd
Generic Use:Ciclosporin
Substitutes:cyclomune 0.1(5ml) , cyclomune 0.1(3ml)

Generic ( Ciclosporin )

Typical use Of Ciclosporin :Organ Transplant
Mechanism of action of Ciclosporin :Ciclosporin Is A Strong Immunosuppressant That Acts Mainly On The Helper T-cells. It Inhibits The Activation Of Calcineurin And Production Of Interleukin-2, Thus Reducing Cell-mediated Immune Response.
Drug Interaction of Ciclosporin :Increased Ciclosporin Level By Diltiazem, Doxycycline, Erythromycin, Ketoconazole, Methylprednisolone (high Doses), Nicardipine, Verapamil, Oral Contraceptives. Drugs Which Reduce Ciclosporin Level Are Carbamazepine, Isoniazid, Phenobarbitone, Phenytoin And Rifampicin. Increased Risk Of Convulsion When Used Concurrently With High-dose Methylprednisolone. Potentially Fatal: Additive Nephrotoxicity When Used With Aminoglycosides, Amphotericin B, Ciprofloxacin, Colchicine, Melphalan, Co-trimoxazole And NSAIDs.
Side effects of Ciclosporin :Hypertension, Hepatoxicity, Hypertrichosis, Facial Oedema, Acne, Gingival Hypertrophy, Hyperkalaemia, Fluid Retention, Increased Susceptibility To Infections, GI Symptoms. Nephrotoxicity; Convulsions.


How Ciclosporin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ciclosporin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Ciclosporin

No Studies Found