Medicine : Cromoplex Forte

Name:Cromoplex Forte
Type:Tablet
Manufacturer:Aristo Pharmaceuticals Pvt Ltd
Generic Use:Cyanocobalamin , Vitamin B6 , Nicotinamide , Folic Acid , Chromium Picolinate
Composition:Cyanocobalamin(10 Mg) , Vitamin B6(3 Mg) , Nicotinamide(50 Mg) , Folic Acid(1 Mg) , Chromium Picolinate(200 Mcg)
Substitutes:cromoplex forte , cromoplex forte , cromoplex forte , cromoplex forte , cromoplex forte


Generic ( Cyanocobalamin )


Typical use Of Cyanocobalamin :Addisonian Pernicious Anaemia, Congenital Cobalamine Malabsorption, Congenital Intrinsic Factor Deficiency, Homocystenemia, Ileal Resection, Methylmalonylacidurias, Nutrition Deficiency, Post Gastrectomy Vit B-12 Deficiency, Transcobalamin II Deficiency, And Can Also Be Given In Adjunctive Therapy As An Alternative Drug Of Choice In Vitamin-B12 Defeciency Of Dietary Origin.
Mechanism of action of Cyanocobalamin :Vitamin B12 Is Used In The Body In Two Forms: Methylcobalamin And 5-deoxyadenosyl Cobalamin. The Enzyme Methionine Synthase Needs Methylcobalamin As A Cofactor. This Enzyme Is Involved In The Conversion Of The Amino Acid Homocysteine Into Methionine. Methionine In Turn Is Required For DNA Methylation. 5-Deoxyadenosyl Cobalamin Is A Cofactor Needed By The Enzyme That Converts L-methylmalonyl-CoA To Succinyl-CoA. This Conversion Is An Important Step In The Extraction Of Energy From Proteins And Fats. Furthermore, Succinyl CoA Is Necessary For The Production Of Hemoglobin, The Substances That Carries Oxygen In Red Blood Cells.
Drug Interaction of Cyanocobalamin :Cyanocobalamin Is Known To Interact With Other Drugs Like Alcohol, Chloramphenicol, Cholestyramine, Colchicine, Colchicine, Epoetin, Glucose, Neomycin, Neomycin, Omeprazole.
Side effects of Cyanocobalamin :Hypersensitivity Reactions, Shivering, Dyspnea, Persistant Urticaria, Bronchospasm.

INTERACTIONS OF CYANOCOBALAMIN

How Cyanocobalamin will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Cyanocobalamin will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Cyanocobalamin

No Studies Found





Generic ( Vitamin B6 )


Typical use Of Vitamin B6 :It Is Used For The Treatment And Prevention Of Vitamin B6 Deficiency. It Is Important For The Breakdown Of Protein, Fats, And Carbohydrates From Foods.
Mechanism of action of Vitamin B6 : Vitamin B6, Principally In Its Biologically Active Coenzyme Form Pyridoxal 5'-phosphate, Is Involved In A Wide Range Of Biochemical Reactions, Including The Metabolism Of Amino Acids And Glycogen, The Synthesis Of Nucleic Acids, Hemogloblin, Sphingomyelin And Other Sphingolipids, And The Synthesis Of The Neurotransmitters Serotonin, Dopamine, Norepinephrine And Gamma-aminobutyric Acid (GABA).
Drug Interaction of Vitamin B6 :Pyridoxine Is Known To Interact With Other Drugs Like Ethionamide, Fosphenytoin, Isoniazid, Levodopa, Nitrofurantoin, Penicillamine, Phenobarbitone, Phenytoin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Vitamin B6 :Nausea, Stomach Upset, Headache, Sleepiness, Tingling, Prickling, Burning Or Sensation Of Tightness.

INTERACTIONS OF VITAMIN B6

How Vitamin B6 will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Vitamin B6 will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Vitamin B6

No Studies Found





Generic ( Nicotinamide )


Typical use Of Nicotinamide :To Treat Inflammatory Skin Disease Like Acne, Anxiety And Alzheimer’s Disease
Mechanism of action of Nicotinamide :Nicotinamide Is A Component Of Two Coenzymes, Which Bring About Tissue Respiration, Lipid, Amino Acid, Protein, And Purine Metabolism. Nicotinamide Lowers Blood Cholesterol And Triglyceride Levels By Inhibiting The Synthesis Of Very Low Density Lipoproteins.
Drug Interaction of Nicotinamide :Nicotinamide Is Known To Interact With Other Drugs Like Carbamazepine, Primidone By Reducing Its Clearance. It Also Interacts With Drugs Like Chloramphenicol, Phenytoin, Methotrexate, Penicillamine, Other Vitamins/nutritional Supplements, Antibiotics Like Ciprofloxacin, Levofloxacin And Tetracyclines. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Nicotinamide :Hepatotoxicity, Cholestasis, Portal Fibrosis, Headache, Fatigue, Urge To Vomit (nausea), Stomach Upset, Dizziness, Dry Hair, Diarrhea, Blurred Vision, Flushing And Rash.

INTERACTIONS OF NICOTINAMIDE

How Nicotinamide will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Nicotinamide will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Nicotinamide

No Studies Found





Generic ( Folic Acid )


Typical use Of Folic Acid :Folic Acid Is A Vitamin Used In The Treatment And Prevention Of Anemia (low Red Blood Cells) Due To Folic Acid Deficiency, Pregnancy Or As A Side Effect Of Certain Drugs, Kidney Disorders, Malabsorption Syndromes, And To Prevent Birth Defects In Infants.
Mechanism of action of Folic Acid :Folic Acid Is Involved In Producing The Genetic Material Called DNA, In Formation Of Red Blood Cells, In Reducing Risk Of Heart Problems (by Reducing Blood Homocysteine Levels) And Other Body Functions.
Drug Interaction of Folic Acid :Fluorouracil, Sulphonamide, Phenytoin, Methotrexate, Sulfasalazine, Cholestyramine, And Zinc May Affect The Efficacy Of Folic Acid Or Vice Versa. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Folic Acid :The Common Side Effects Are Urge To Vomit, Bloating Of Stomach, Excessive Passage Of Wind, Loss Of Appetite, Worsening Of Vitamin B12 Deficiency (when Folic Acid Is Used Alone To Treat Anemia Without Investigating The Cause). Consult Your Doctor Immediately If Rash, Itching, Or Breathlessness Develops.

INTERACTIONS OF FOLIC ACID

How Folic Acid will impact on Pregnancy ?

There Is Sufficient Evidence To Suggest That There Is No Risk To The Fetus In The First Trimester (12 Weeks) Of Pregnancy And There Is No Evidence Of Risk In Later Trimesters. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Folic Acid will impact during lactation(breastfeeding) ?

Safest: Evidence From Clinical Studies Has Shown That This Drug When Taken By Breastfeeding Mothers Has Not Shown Any Major Side Effects In Infants. The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare Or The Drug Does Not Reach The Infant Through Breast Milk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Folic Acid

No Studies Found





Generic ( Chromium Picolinate )


Typical use Of Chromium Picolinate :Chromium Deficiency, Which Is Very Rare.Used In Very Sick Patients With Improrper Nutrition.
Mechanism of action of Chromium Picolinate :This Medication Is A Sulfonylurea Antidiabetic Drug, Prescribed For Type 2 Diabetes. This Medication Helps To Keep Blood Sugar Levels Under Control.
Drug Interaction of Chromium Picolinate :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Chromium Picolinate :Skin Rash And Acute Toxicity.

INTERACTIONS OF CHROMIUM PICOLINATE

How Chromium Picolinate will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chromium Picolinate will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Chromium Picolinate

No Studies Found