Medicine : Coscold Syp(60ml)

Name:Coscold Syp(60ml)
Type:Syrup
Manufacturer:Adcock Ingram
Generic Use:Phenylephrine Hydrochloride , Chlorpheniramine Maleate , Paracetamol
Composition:Phenylephrine Hydrochloride(5 Mg) , Chlorpheniramine Maleate(2 Mg) , Paracetamol(125mg /5ml)
Substitutes:coscold syp(60ml) , coscold syp(60ml) , coscold syp(60ml)


Generic ( Phenylephrine Hydrochloride )


Typical use Of Phenylephrine Hydrochloride :Acid-related Dyspepsia, Congestion, Hypotension.
Mechanism of action of Phenylephrine Hydrochloride :Phenylephrine Is A Sympathomimetic With Mainly Direct Effects On Alpha-adrenergic Receptors And Weak Beta-adrenergic Activity. It Causes Vasoconstriction Of The Arterioles Of The Nasal Mucosa And Conjunctiva; Activates The Dilator Muscle Of The Pupil To Cause Contraction; Produces Vasoconstriction Of Arterioles In The Body And Produces Systemic Arterial Vasoconstriction.
Drug Interaction of Phenylephrine Hydrochloride :May Increase Hypertensive Effect Of Beta-blockers (nonselective).
Side effects of Phenylephrine Hydrochloride :Anxiety, Reflex Bradycardia, Tachycardia, Arrhythmias, Headache, Cold Extremities.

INTERACTIONS OF PHENYLEPHRINE HYDROCHLORIDE

How Phenylephrine Hydrochloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Phenylephrine Hydrochloride will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Phenylephrine Hydrochloride

No Studies Found





Generic ( Chlorpheniramine Maleate )


Typical use Of Chlorpheniramine Maleate :For The Treatment Of Rhinitis, Urticaria, Allergy, Common Cold, Asthma And Hay Fever.
Mechanism of action of Chlorpheniramine Maleate :Chlorphenamine Is An H1-receptor Antagonist Which Competetively Blocks H1-receptor Sites On Tissues.
Drug Interaction of Chlorpheniramine Maleate :Avoid Excessive Alcohol Consumption. Anticholinergic Effects Of Chlorphenamine (e.g. Dry Mouth, Blurred Vision) May Be Enhanced By Drugs With Anticholinergic Effects Such As Antipsychotics, MAOI Or Tricyclic Antidepressants. Chlorphenamine Inhibits Phenytoin Metabolism And Can Lead To Phenytoin Toxicity.
Side effects of Chlorpheniramine Maleate :Blurred Vision, Dry Eyes, Mydriasis, Drowsiness, Fatigue, Headache, Dizziness, Psychomotor Impairment, Dry Mouth, Gastrointestinal Disturbances.

INTERACTIONS OF CHLORPHENIRAMINE MALEATE

How Chlorpheniramine Maleate will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chlorpheniramine Maleate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Chlorpheniramine Maleate

No Studies Found





Generic ( Paracetamol )


Typical use Of Paracetamol :Paracetamol Is Used For The Relief Of Mild To Moderate Pain In Conditions Such As Headache (including Migraine), Toothache, Ear Pain, Joint Pain, Pain Of Menstruation, Fever, Feverish Colds, And Flu.
Mechanism of action of Paracetamol :Paracetamol Is Categorized As An Analgesic (painkiller) And Antipyretic (fever Reducing) Drug. Paracetamol Reduces Pain By Increasing The Pain Threshold. It Reduces Fever By Acting On The Temperature-regulating Region Of Brain, Resulting In Increased Blood Flow Across The Skin, Sweating And Heat Loss.
Drug Interaction of Paracetamol :Cholestyramine, Metoclopramide And Domperidone May Alter The Effects Of Paracetamol. Use Of Paracetamol With Warfarin May Increase The Risk Of Bleeding. Paracetamol May Increase The Effects Of Chloramphenicol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Paracetamol :Side Effects Of Paracetamol Are Usually Rare, And Include Allergic Reactions Such As Shortness Of Breath, Abnormalities Of Blood Cells, Skin Reddening, Blisters Or Rash, Swollen Facial Features, Or A Runny Nose. Overdose (more Than 4 G In Adults And More Than 2 G In Children) May Cause Severe Liver Damage.

INTERACTIONS OF PARACETAMOL

How Paracetamol will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Paracetamol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Paracetamol

No Studies Found