Medicine : Codomolindon

Manufacturer:Zydus Cadila
Generic Use:Codeine , Paracetamol
Composition:Codeine(10mg) , Paracetamol(500mg)
Substitutes:codomolindon , codomolindon

Generic ( Codeine )

Typical use Of Codeine :Mild To Moderate Pain; Diarrhoea ; Cough Suppression
Mechanism of action of Codeine :Codeine Provides Relief By Blocking The Ascending Pain Pathways By Binding To Opiate Receptors Found In The CNS. It Also Helps Suppress Cough By Direct Action In The Medulla.
Drug Interaction of Codeine :Enhanced Depressant Effects With Alcohol, Anaesthetics, Anxiolytics, Hypnotics, TCAs, Antipsychotics. Possible CNS Depression Or Excitation With MAOIs. May Alter Effects Of Other Compounds E.g. Cyclizine, Mexiletine, Cisapride, Metoclopramide And Domperidone.
Side effects of Codeine :Dependence, Withdrawal Symptoms; Nausea, Vomiting, Constipation; Drowsiness, Confusion; Difficulty In Micturition, Ureteric Or Biliary Spasms, Urinary Retention; Dry Mouth, Dizziness, Sweating, Facial Flushing, Headache, Vertigo, Bradycardia, Tachycardia, Palpitations, Orthostatic Hypotension, Hypothermia, Restlessness, Mood Changes, Decreased Libido Or Potency, Hallucination, Miosis; Raised Intracranial Pressure, Muscle Rigidity.


How Codeine will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Codeine will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Codeine

No Studies Found

Generic ( Paracetamol )

Typical use Of Paracetamol :Paracetamol Is Used For The Relief Of Mild To Moderate Pain In Conditions Such As Headache (including Migraine), Toothache, Ear Pain, Joint Pain, Pain Of Menstruation, Fever, Feverish Colds, And Flu.
Mechanism of action of Paracetamol :Paracetamol Is Categorized As An Analgesic (painkiller) And Antipyretic (fever Reducing) Drug. Paracetamol Reduces Pain By Increasing The Pain Threshold. It Reduces Fever By Acting On The Temperature-regulating Region Of Brain, Resulting In Increased Blood Flow Across The Skin, Sweating And Heat Loss.
Drug Interaction of Paracetamol :Cholestyramine, Metoclopramide And Domperidone May Alter The Effects Of Paracetamol. Use Of Paracetamol With Warfarin May Increase The Risk Of Bleeding. Paracetamol May Increase The Effects Of Chloramphenicol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Paracetamol :Side Effects Of Paracetamol Are Usually Rare, And Include Allergic Reactions Such As Shortness Of Breath, Abnormalities Of Blood Cells, Skin Reddening, Blisters Or Rash, Swollen Facial Features, Or A Runny Nose. Overdose (more Than 4 G In Adults And More Than 2 G In Children) May Cause Severe Liver Damage.


How Paracetamol will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Paracetamol will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Paracetamol

No Studies Found