Generic ( Codeine )
|Typical use Of Codeine :||Mild To Moderate Pain; Diarrhoea ; Cough Suppression|
|Mechanism of action of Codeine :||Codeine Provides Relief By Blocking The Ascending Pain Pathways By Binding To Opiate Receptors Found In The CNS. It Also Helps Suppress Cough By Direct Action In The Medulla.|
|Drug Interaction of Codeine :||Enhanced Depressant Effects With Alcohol, Anaesthetics, Anxiolytics, Hypnotics, TCAs, Antipsychotics. Possible CNS Depression Or Excitation With MAOIs. May Alter Effects Of Other Compounds E.g. Cyclizine, Mexiletine, Cisapride, Metoclopramide And Domperidone.|
|Side effects of Codeine :||Dependence, Withdrawal Symptoms; Nausea, Vomiting, Constipation; Drowsiness, Confusion; Difficulty In Micturition, Ureteric Or Biliary Spasms, Urinary Retention; Dry Mouth, Dizziness, Sweating, Facial Flushing, Headache, Vertigo, Bradycardia, Tachycardia, Palpitations, Orthostatic Hypotension, Hypothermia, Restlessness, Mood Changes, Decreased Libido Or Potency, Hallucination, Miosis; Raised Intracranial Pressure, Muscle Rigidity.|
INTERACTIONS OF CODEINE
How Codeine will impact on Pregnancy ?Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Codeine will impact during lactation(breastfeeding) ?Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
Medicine & Alcohol use and effect of CodeineNo Studies Found