Medicine : Cloxide Plus

Name:Cloxide Plus
Type:Tablet
Manufacturer:La Pharmaceuticals
Generic Use:Chlordiazepoxide , Trifluoperazine
Composition:Chlordiazepoxide(10mg) , Trifluoperazine(1MG)
Substitutes:fit eye , cloxide plus , serepose , cloact , fit eye , cloxide plus , serepose , cloact


Generic ( Chlordiazepoxide )



Typical use Of Chlordiazepoxide :Acute Alcohol Withdrawal, Adjunct In Acute Alcohol Withdrawal, Adjunt In Acute Alcohol Withdrawal, Anxiety, Dysmenorrhoea, Insomnia, Muscular Spasm, Premedication In Anaesthesia, Psychosomatic Disorders.
Mechanism of action of Chlordiazepoxide :Chlordiazepoxide Enhances Activity Of The Inhibitory Transmitter GABA In Different Parts Of CNS By Increasing Neuronal-membrane Permeability To Chloride Ions Resulting To Hyperpolarisation And Stabilisation. It Has Some Muscle Relaxant And Anticonvulsant Activity.
Drug Interaction of Chlordiazepoxide :Chlordiazepoxide Is Known To Interact With Other Drugs Like Alcohol, Aluminium Hydroxide And Oxide, Atropine (Sulphate), Cimetidine (HCl), Human Insulin, Insulin Lispro, Iprindole. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Chlordiazepoxide :Psychological Impairment, Cerebral Atrophy, Psychomotor Performance Impairment, Hemolytic Anemia, Hypoplastic Anemia, Skin Reactions, Aggression, Dependence.

INTERACTIONS OF CHLORDIAZEPOXIDE


How Chlordiazepoxide will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chlordiazepoxide will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Chlordiazepoxide

No Studies Found






Generic ( Trifluoperazine )



Typical use Of Trifluoperazine :Agitation, Anxiety, Diagnostic Procedures, Enhance Permeation Of SC Or IM Inj, Muscle Spasm Of Varied Aeitology, Nausea And Vomiting, Psychosis, Schizophrenia, Severe Nausea And Vomiting.
Mechanism of action of Trifluoperazine :Trifluoperazine Blocks Postsynaptic Mesolimbic Dopaminergic D1 And D2 Receptors In The Brain; Depresses The Release Of Hypothalamic And Hypophyseal Hormones And Is Believed To Depress The Reticular Activating System Thus Affecting Basal Metabolism, Body Temperature, Wakefulness, Vasomotor Tone, And Emesis.
Drug Interaction of Trifluoperazine :Trifluoperazine Is Known To Interact With Other Drugs Like Adrenaline, Alcohol, Guanethidine, Levodopa, Thyroxine (Na), Trazodone (HCl). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictlybe Required.
Side effects of Trifluoperazine :Tardive Dyskinesia, Hypotension, Akathisia, Torticollis, Dystonic Syndrome, Dizziness, Drowsiness, Anorexia,insomnia, Dry Mouth, Blurred Vision, Postural Hypotension, Lassitude, Motor Restlessnes, Dyskinesia, Dystonia.

INTERACTIONS OF TRIFLUOPERAZINE


How Trifluoperazine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Trifluoperazine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Trifluoperazine

No Studies Found