Medicine : Clovate Skin(50gm)
|Manufacturer:||Dermocare Laboratories Gujarat Pvt Ltd|
|Generic Use:||Clobetasole Propionate|
|Composition:||Clobetasole Propionate(0.5%w /w)|
|Substitutes:||clovate skin(10gm) , clovate skin(30gm) , clovate skin(50gm)|
Generic ( Clobetasole Propionate )
|Typical use Of Clobetasole Propionate :||Skin Infection|
|Mechanism of action of Clobetasole Propionate :||The Precise Mechanism Of The Antiinflammatory Activity Of Topical Steroids In The Treatment Of Steroid-responsive Dermatoses, In General, Is Uncertain. However, Corticosteroids Are Thought To Act By The Induction Of Phospholipase A2 Inhibitory Proteins, Collectively Called Lipocortins. It Is Postulated That These Proteins Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes By Inhibiting The Release Of Their Common Precursor Arachidonic Acid. Arachidonic Acid Is Released From Membrane Phospholipids By Phospholipase A2. Initially, However, Clobetasol, Like Other Corticosteroids, Bind To The Glucocorticoid Receptor, Which Complexes, Enteres The Cell Nucleus And Modifies Genetic Transcription (transrepression/transactivation).|
|Drug Interaction of Clobetasole Propionate :||If Overdose Is Suspected, Contact Your Physician.|
|Side effects of Clobetasole Propionate :||Headache, Fatigue, Nausea, Constipation, Dry Mouth, Sedation, Skin Rash, Gastralgia.|
INTERACTIONS OF CLOBETASOLE PROPIONATE
How Clobetasole Propionate will impact on Pregnancy ?Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
How Clobetasole Propionate will impact during lactation(breastfeeding) ?Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.
Medicine & Alcohol use and effect of Clobetasole PropionateNo Studies Found