Medicine : Clindoxyl (10gm)

Name:Clindoxyl (10gm)
Type:Cream
Manufacturer:Stiefel India Pvt Ltd
Generic Use:Benzoyl Peroxide , Clindamycin Phosphate
Composition:Benzoyl Peroxide(1 % W/w) , Clindamycin Phosphate(1 % W/w)
Substitutes:clindoxyl (10gm) , clindoxyl (10gm)


Generic ( Benzoyl Peroxide )



Typical use Of Benzoyl Peroxide :Acne Vulgaris And Acne Rosacea.
Mechanism of action of Benzoyl Peroxide :Benzoyl Peroxide Has Mild Keratolytic Effect And Antimicrobial Activity Which Is Attributed To Its Oxidative Property. It Is Active Against S.epidermidis And P.acne.
Drug Interaction of Benzoyl Peroxide :PABA Sunscreens May Transiently Discolour Fabric.
Side effects of Benzoyl Peroxide :Excessive Drying Of Skin, Allergic Dermatitis. May Bleach Fabrics Or Hair. Skin Discoloration; Skin Rash, Peeling, Transient Local Oedema.

INTERACTIONS OF BENZOYL PEROXIDE


How Benzoyl Peroxide will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Benzoyl Peroxide will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Benzoyl Peroxide

No Studies Found






Generic ( Clindamycin Phosphate )



Typical use Of Clindamycin Phosphate : Acne Vulgaris, Babesiosis, Bacterial Infections, Bacterial Vaginosis, Dental Infections, Endocarditis, Hidradenitis Suppurativa, Intra-abdominal Infections, Malaria, Osteomyelitis, Pelvic Infections, Peritonitis, Pulmonary Infection, Septic Arthritis, Septicaemia.
Mechanism of action of Clindamycin Phosphate :Clindamycin Inhibits Protein Synthesis Of Bacteria By Binding To The 50S Ribosomal Subunits Of The Bacteria. Specifically, It Binds Primarily To The 23S RNA Subunit. Topical Clindamycin Reduces Free Fatty Acid Concentrations On The Skin And Suppresses The Growth Of Propionibacterium Acnes (Corynebacterium Acnes) , An Anaerobe Found In Sebaceous Glands And Follicles.
Drug Interaction of Clindamycin Phosphate :Clindamycin Is Known To Interact With Other Drugs Like Bamifylline, Calcium Gluconate, Distigmine (Br), Gentamicin, Lincomycin (HCl), Pancuronium (Br), Physostigmine, Rivastigmine, Rocuronium (Br), Sodium Thiosulphate. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Clindamycin Phosphate :Elevated SGPT & SGOT, Elevated Alkaline Phosphatase Concentration, Esophageal Ulceration, Severe Diarrhea, Ventricular Fibrillation, Anaphylactic Shock, Pseudomembranous Colitis, Cardiac Arrest, Colonic Ulceration, Mucosal Edema, Nausea, Vomiting, Abdominal Pain, Rashes, Vaginitis, Contact Dermatitis, Leukocytoclastic Angiitis, Local Irritation.

INTERACTIONS OF CLINDAMYCIN PHOSPHATE


How Clindamycin Phosphate will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clindamycin Phosphate will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Clindamycin Phosphate

No Studies Found