Medicine : Clarinova (250mg)

Name:Clarinova (250mg)
Manufacturer:Mankind Pharma
Generic Use:Clarithromycin
Composition:Clarithromycin(250 Mg)

Generic ( Clarithromycin )

Typical use Of Clarithromycin :URTI, Pharyngitis And Sinusitis, LRTI, Bronchitis And Pneumonia, Skin And Soft Tissue Infection. H.Pylori Infection.Infection Due To Mycobacterium Avium Complex (MAC).
Mechanism of action of Clarithromycin :Clarithromycin Is First Metabolized To 14-OH Clarithromycin, Which Is Active And Works Synergistically With Its Parent Compound. Like Other Macrolides, It Then Penetrates Bacteria Cell Wall And Reversibly Binds To Domain V Of The 23S Ribosomal RNA Of The 50S Subunit Of The Bacterial Ribosome, Blocking Translocation Of Aminoacyl Transfer-RNA And Polypeptide Synthesis. Clarithromycin Also Inhibits The Hepatic Microsomal CYP3A4 Isoenzyme And P-glycoprotein, An Energy-dependent Drug Efflux Pump.
Drug Interaction of Clarithromycin :Clarithromycin Is Known To Interact With Other Drugs Like Alprazolam, Artesunate, Astemizole, Carbamazepine, Cimetidine (HCl), Cisapride, Cyclosporin A, Digoxin, Dihydroergotamine (Mesylate), Disopyramide, Ergotamine (Tartrate), Erlotinib, Fluoxetine (HCl), Isosorbide (Dinitrate), Loratadine, Lorazepam, Lovastatin.
Side effects of Clarithromycin :Pseudomembranous Colitis, Renal Failure, Interstitial Nephritis, Headache, Nausea, Vomiting, Diarrhea, Abdominal Pain, Phlebitis, Glossitis, Stomatitis.


How Clarithromycin will impact on Pregnancy ?

Information Not Available.

How Clarithromycin will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Clarithromycin

Information Not Available.