Medicine : Citafine (200mg)

Name:Citafine (200mg)
Manufacturer:Emcure Pharmaceuticals Ltd
Generic Use:Gemcitabine
Composition:Gemcitabine(200 Mg)

Generic ( Gemcitabine )

Typical use Of Gemcitabine :Locally Advanced Or Metastatic Pancreatic Cancer, Lung Cancer, Lung Cancer And Pancreatic Cancer, Pancreatic Cancer, Treatment Of Locally Advanced Or Metastatic Pancreatic Cancer.
Mechanism of action of Gemcitabine :Gemcitabine Inhibits Thymidylate Synthetase, Leading To Inhibition Of DNA Synthesis And Cell Death. Gemcitabine Is A Prodrug So Activity Occurs As A Result Of Intracellular Conversion To Two Active Metabolites, Gemcitabine Diphosphate And Gemcitabine Triphosphate By Deoxycitidine Kinase. Gemcitabine Diphosphate Also Inhibits Ribonucleotide Reductase, The Enzyme Responsible For Catalyzing Synthesis Of Deoxynucleoside Triphosphates Required For DNA Synthesis. Finally, Gemcitabine Triphosphate (diflurorodeoxycytidine Triphosphate) Competes With Endogenous Deoxynucleoside Triphosphates For Incorporation Into DNA.
Drug Interaction of Gemcitabine :Not Reported.
Side effects of Gemcitabine :Alopecia, Diarrhea, Fever, Constipation, Rashes, StomatitisX, Nausea And Vomiting, Thrombocytopenia, Neutropenia, Anemia, Leukopenia.


How Gemcitabine will impact on Pregnancy ?

Information Not Available.

How Gemcitabine will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Gemcitabine

Information Not Available.