Medicine : Chloramsone

Name:Chloramsone
Type:Drop
Manufacturer:Ranbaxy Laboratories Ltd
Generic Use:Benzalkonium Chloride , Chloramphenicol , Prednisolone
Composition:Benzalkonium Chloride(0.002%W/V) , Chloramphenicol(0.2%W/V) , Prednisolone()
Substitutes:chloramsone , chloramsone , chloramsone


Generic ( Benzalkonium Chloride )



Typical use Of Benzalkonium Chloride :Bladder Irrigation, Ear, Eye, Nose And Throat Irrigation, Gingivitis, Perodontal Diseases, Preoperative Disinfection Of Unbroken Skin, Stomatitis, Thrush, Tonsillitis, Urethral Irrigation.
Mechanism of action of Benzalkonium Chloride :The Mode Of Action Of Benzalkonium Chloride Appears To Be Associated With The Effect On The Cytoplasmic Membrane, Which Controls Cell Permeability.
Drug Interaction of Benzalkonium Chloride :Tell Your Doctor Of All Prescription And Nonprescription Medication You May Use. Do Not Start Or Stop Any Medicine Without Doctor Or Pharmacist Approval.
Side effects of Benzalkonium Chloride : Death, Vomiting, Convulsions, Coma, Collapse, Restlessness, Muscular Weakness, Cyanosis, Dyspnea, Apprehension, Paralysis Of Respiratory Muscle, Allergic Contact Dermatitis.

INTERACTIONS OF BENZALKONIUM CHLORIDE


How Benzalkonium Chloride will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Benzalkonium Chloride will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Benzalkonium Chloride

No Studies Found






Generic ( Chloramphenicol )



Typical use Of Chloramphenicol :Enteric Fever (Typhoid And Para Typhoid).H.Influenzae Meningitis. Anaerobic Infections, Intraocular Infections, Urinary Tract Infections, Conjunctivitis, External Ear Infections.Corneal Ulcer, Bacterial Conjunctivitis, Trachoma, Ocular Infections.Otitis Externa, Chronic Otitis Media. Pre And Post Antral Or Mastoid Surgery.
Mechanism of action of Chloramphenicol :Chloramphenicol Is Lipid-soluble, Allowing It To Diffuse Through The Bacterial Cell Membrane. It Then Reversibly Binds To The L16 Protein Of The 50S Subunit Of Bacterial Ribosomes, Where Transfer Of Amino Acids To Growing Peptide Chains Is Prevented (perhaps By Suppression Of Peptidyl Transferase Activity), Thus Inhibiting Peptide Bond Formation And Subsequent Protein Synthesis.
Drug Interaction of Chloramphenicol :Chloramphenicol Is Known To Interact With Other Drugs Like Amoxicillin, Ampicillin, Ascorbic Acid, Azlocillin (Na), Bacampicillin, Benzathine Penicillin, Carbenicillin (Na), Chlorpropamide, Chymotrypsin, Cimetidine (HCl), Ciprofloxacin, Cloxacillin, Clozapine, Colistin (Sulphate & Sulphomethate Na), Cyanocobalamin, Cyclophosphamide, Dicloxacillin (Na), Ethinyloestradiol, Floxacillin (Na), Fosphenytoin, Estodene, Glibornuride, Gliquidone, Hydroxocobalamin, Ichthammol, Iron Dextran, Iron Salts, Iron Sorbitol, Mecillinam, Mecobalamin, Nafcillin, Oxacillin, Paracetamol, Phenobarbitone, Phenytoin (Na), Piperacillin (Na),pivmecillinam (HCl), Primidone, Procaine Penicillin, Promethazine (HCl),rifampicin, Sulfapyridine, Tolbutamide, Warfarin (Na).
Side effects of Chloramphenicol :Encephalopathy, Pseudomembranous Colitis, Anemia, Urticaria, Anemia, Thrombocytopenia, Hepatitis, Ototoxicity, Peripheral Neuropathy, Optic Neuritis, Hemolytic Reactions, Interstitial Nephritis, Headache, Nausea, Vomiting, Maculopapular Rash, Stomatitis, Confusion, Pruritus, Depression, Glossitis, Delirium, Transient Stinging.

INTERACTIONS OF CHLORAMPHENICOL


How Chloramphenicol will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Chloramphenicol will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Chloramphenicol

No Studies Found






Generic ( Prednisolone )



Typical use Of Prednisolone :Adrenal Insufficiency, Asthma, Blood Malignancies, Connective Tissue Diseases, Liver Diseases, Ocular Diseases, Renal Diseases, Respiratory Disease, Suppression Of Inflammatory And Allergic Disorders.
Mechanism of action of Prednisolone :Glucocorticoids Such As Prednisolone Can Inhibit Leukocyte Infiltration At The Site Of Inflammation, Interfere With Mediators Of Inflammatory Response, And Suppress Humoral Immune Responses. The Antiinflammatory Actions Of Glucocorticoids Are Thought To Involve Phospholipase A2 Inhibitory Proteins, Lipocortins, Which Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes. Prednisolone Reduces Inflammatory Reaction By Limiting The Capillary Dilatation And Permeability Of The Vascular Structures. These Compounds Restrict The Accumulation Of Polymorphonuclear Leukocytes And Macrophages And Reduce The Release Of Vasoactive Kinins.
Drug Interaction of Prednisolone :Rifampin Decreases Blood Levels Of Prednisolone By Increasing Its Breakdown In The Liver. The Dose Of Prednisolone May Need To Be Increased In Order To Avoid Therapeutic Failure. Corticosteroids Have Variable Effects Of Warfarin (Coumadin) Therapy. Coagulation Levels Should Be Monitored More Closely When Anticoagulants Are Combined With Corticosteroids. Estrogens May Increase The Levels Of Prednisolone By Decreasing Its Breakdown. When Estrogens Are Used With Prednisolone, Side Effects Of Prednisolone Should Be Monitored.
Side effects of Prednisolone :On Long Term Use Cushing's Syndrome And Growth Retardation In Childn; Osteoporosis, Fractures. Peptic Ulceration; Glaucoma, Cataract May Occur.

INTERACTIONS OF PREDNISOLONE


How Prednisolone will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Prednisolone will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Prednisolone

No Studies Found