Medicine : Cans Lb Suppository

Name:Cans Lb Suppository
Type:Suppository
Manufacturer:Ravenbhel Healthcare Pvt Ltd
Generic Use:Clindamycin , Miconazole
Composition:Clindamycin(100mg) , Miconazole(200mg)
Substitutes:cans lb suppository , cans lb suppository


Generic ( Clindamycin )



Typical use Of Clindamycin :Acne Vulgaris, Babesiosis, Bacterial Infections, Bacterial Vaginosis, Dental Infections, Endocarditis, Hidradenitis Suppurativa, Intra-abdominal Infections, Malaria, Osteomyelitis, Pelvic Infections, Peritonitis, Pulmonary Infection, Septic Arthritis, Septicaemia.
Mechanism of action of Clindamycin :Systemic/vaginal Clindamycin Inhibits Protein Synthesis Of Bacteria By Binding To The 50S Ribosomal Subunits Of The Bacteria. Specifically, It Binds Primarily To The 23s RNA Subunit. Topical Clindamycin Reduces Free Fatty Acid Concentrations On The Skin And Suppresses The Growth Of Propionibacterium Acnes (Corynebacterium Acnes) , An Anaerobe Found In Sebaceous Glands And Follicles.
Drug Interaction of Clindamycin :Clindamycin Is Known To Interact With Other Drugs Like Bamifylline, Calcium Gluconate, Distigmine (Br), Gentamicin, Lincomycin (HCl), Pancuronium (Br), Physostigmine, Rivastigmine, Rocuronium (Br), Sodium Thiosulphate.
Side effects of Clindamycin :Elevated SGPT & SGOT, Elevated Alkaline Phosphatase Concentration, Esophageal Ulceration, Pseudomembranous Colitis, Cardiac Arrest, Colonic Ulceration, Nausea, Vomiting, Abdominal Pain, Rashes, Vaginitis, Contact Dermatitis.

INTERACTIONS OF CLINDAMYCIN


How Clindamycin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clindamycin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Clindamycin

No Studies Found






Generic ( Miconazole )



Typical use Of Miconazole :Vulvo-vaginal Candidiasis, Balanitis.Tinea Vapitis, T Corporis, T Manuum, T Pedis (atheletes Foot), T Barbae, T Cruris, T Unguium Or Onychomycosis, Pityriasis Versicolor.Candidiasis Of Skin And Nails.
Mechanism of action of Miconazole :Miconazole Interacts With 14-? Demethylase, A Cytochrome P-450 Enzyme Necessary To Convert Lanosterol To Ergosterol, Causes Inhibition Of Ergosterol Synthesis Results In Increased Cellular Permeability Causing Leakage Of Cellular Contents. Miconazole May Also Inhibit Endogenous Respiration, Interact With Membrane Phospholipids, Inhibit The Transformation Of Yeasts To Mycelial Forms, Inhibit Purine Uptake, And Impair Triglyceride And/or Phospholipid Biosynthesis.
Drug Interaction of Miconazole :Miconazole (Nitrate) Is Known To Interact With Other Drugs Like Alprazolam, Amphotericin B,astemizole, Carbamazepine, Cisapride, Fosphenytoin, Phenytoin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Miconazole :Cardiac Arrhythmias, Phlebitis, Pruritis, Arachnoiditis, Cardiac Arrest, Anaphylaxis, Drowsiness, Anorexia, Rashes, GI Upset, Flushing, Nausea And Vomiting

INTERACTIONS OF MICONAZOLE


How Miconazole will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Miconazole will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Miconazole

No Studies Found