Medicine : Brilinta

Manufacturer:Astra Zeneca
Generic Use:Ticagrelor

Generic ( Ticagrelor )

Typical use Of Ticagrelor :Atherothrombotic Event.
Mechanism of action of Ticagrelor :Ticagrelor Blocks Adenosine Diphosphate (ADP) Receptors Of Subtype P2Y12. In Contrast To The Other Antiplatelet Drugs, Ticagrelor Has A Binding Site Different From ADP, Making It An Allosteric Antagonist, And The Blockage Is Reversible. Moreover, The Drug Does Not Need Hepatic Activation, Which Might Work Better For Patients With Genetic Variants Regarding The Enzyme CYP2C19
Drug Interaction of Ticagrelor :Ticagrelor Is Known To Interact With Other Drugs Like Cisapride, Digoxin, Diltiazem (HCl), Ketoconazole, Rifampicin, Simvastatin. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Ticagrelor :GI Toxicity, Ventricular Pauses, Dyspnea, Hyperuricemia, GI Hemorrhage, Epistaxis, Intracranial Hemorrhage, Dermal Bleeding.


How Ticagrelor will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Ticagrelor will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Ticagrelor

No Studies Found