Medicine : Blumox Dxl

Name:Blumox Dxl
Type:Capsule
Manufacturer:Blue Cross Laboratories Ltd
Generic Use:Fluconazole , Tinidazole
Composition:Fluconazole(150mg) , Tinidazole(1g)
Substitutes:fluzont , cancapkit , blumox dxl , zocont kit , zocon t kit tabs , fluzont , cancapkit , blumox dxl , zocont kit , zocon t kit tabs


Generic ( Fluconazole )



Typical use Of Fluconazole :To Treat Fungal Infections, Including Yeast Infections Of The Vagina, Mouth, Throat, Esophagus (food Pipe), Abdomen, Lungs, Blood, And Other Organs. Fluconazole Is Also Used To Treat Meningitis (infection Of The Membranes Covering The Brain And Spine) Caused By Fungus.
Mechanism of action of Fluconazole :Fluconazole Interacts With Enzymes (14-α Demethylase; Cytochrome P-450) And Prevents The Synthesis Of Ergosterol (an Essential Component Of Fungal Cell Membrane). Inhibition Of Ergosterol Synthesis Results In Increased Cellular Permeability Causing Leakage Of Cellular Contents From Fungal Cell And Ultimately Preventing The Growth Of Fungi.
Drug Interaction of Fluconazole :Fluconazole Is Known To Interact With Other Drugs Like Anesthetic (alfentanil), Aliskiren, Benzodiazepines (midazolam, Triazolam Alprazolam), Anti-depressant (amitriptyline, Nortriptyline), Artesunate, Pimozide, Astemizole, Bosentan, Celecoxib, Chlorpropamide, Cisapride, Cyclosporin A, Fosphenytoin, Hydrochlorothiazide, Blood Pressure Medications (nifedipine, Isradipine, Amlodipine, Felodipine And Losartan), Cholesterol Lowering Medicines (atorvastatin, Simvastatin And Fluvastatin) And Antibiotics Such As Erythromycin. There Are Other Drugs Which May Also Interact With Fluconazole. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Fluconazole :Liver Dysfunction (elevated Liver Enzymes), Loss Of Appetite, Jaundice, Dizziness, Headache, Urge To Vomit (nausea), Vomiting, Stomach Pain And Discomfort, Rashes, Itching All Over The Body, Reddening Of The Skin Or Itchy Red Spots, Hair Loss, Low Potassium Levels (hypokalemia), Paleness In The Face And Low White Blood Cells.

INTERACTIONS OF FLUCONAZOLE


How Fluconazole will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Fluconazole will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Fluconazole

No Studies Found






Generic ( Tinidazole )



Typical use Of Tinidazole :Abdominal Surgery Prophylaxis, Acute Leukemia, Amoebiasis, Anaerobic Infections, Giardiasis, NSAID-associated Ulceration, Prophylaxis Of Acid Aspiration In Obstetric Patients, Trichomoniasis, Upper Gastro-intestinal And Breast Cancer.
Mechanism of action of Tinidazole :The Nitro Group Of Tinidazole Is Reduced In Trichomonas By A Ferredoxin-mediated Electron Transport System. The Free Nitro Radical Generated As A Result Of This Reduction Is Believed To Be Responsible For The Antiprotozoal Activity. The Toxic Free Radicals Covalently Bind To DNA, Causing DNA Damage And Leading To Cell Death.
Drug Interaction of Tinidazole :Tinidazole Is Known To Interact With Other Drugs Like Alcohol. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Tinidazole :Hypotension, Dyspnea, Bronchospasm, Facial Edema, Laryngeal Edema, Headache, Nausea, Vomiting, Urticaria, Thrombophlebitis, Metallic Taste.

INTERACTIONS OF TINIDAZOLE


How Tinidazole will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Tinidazole will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Tinidazole

No Studies Found