Medicine : Biogladin (500mcg)

Name:Biogladin (500mcg)
Manufacturer:United Biotech Pvt Ltd
Generic Use:Alprostadil
Composition:Alprostadil(500 Mcg)
Substitutes:prostin vr(500mcg) , biogladin (500mcg)

Generic ( Alprostadil )

Typical use Of Alprostadil :Adjunctive Therapy, Patency Of Ductus Arteriosus, Patent Ductus Arteriosis.
Mechanism of action of Alprostadil :Alprostadil Causes Vasodilation By Means Of A Direct Effect On Vascular And Ductus Arteriosus (DA) Smooth Muscle. By Its Effect On DA Smooth Muscle, Alprostadil Prevents Or Reverses The Functional Closure Of The DA That Occurs Shortly After Birth, Which Results In Increased Pulmonary Or Systemic Blood Flow In Infants With Impairment Of This Blood Flow. A Reduction In Pulmonary Vascular Resistance Improve Pulmonary Perfusion In Neonates In Whom Congenital Heart Disease Is Associated With Increased Pulmonary Vascular Resistance. In Cyanotic Congenital Heart Disease, Alprostadil's Actions Result In An Increased Oxygen Supply To The Tissues.
Drug Interaction of Alprostadil :Alprostadil Is Known To Interact With Other Drugs Like Captopril, Clonidine (HCl), Diazoxide, Enalapril (Maleate), Glyceryl Trinitrate, Hydralazine (HCl), Losartan (K), Methyldopa, Moxonidine, Prazosin, Propranolol (HCl), Quinapril, Ramipril, Verapamil (HCl). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Alprostadil :Apnea, Seizures, Severe Hypotension, Dizziness, Diarrhea, Abdominal Cramps, Flushing, Reaction At Injection Site.


How Alprostadil will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Alprostadil will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Alprostadil

No Studies Found