Medicine : Bigspas D Inj(2ml)

Name:Bigspas D Inj(2ml)
Manufacturer:Mankind Pharma
Generic Use:Diclofenac Sodium , Camylofine
Composition:Diclofenac Sodium(25 Mg) , Camylofine(25 Mg)
Substitutes:bigspas d inj(2ml) , bigspas d inj(2ml)

Generic ( Diclofenac Sodium )

Typical use Of Diclofenac Sodium :Bacterial Eye Infections And Inflammation
Mechanism of action of Diclofenac Sodium :This Medication Is An NSAID, Prescribed For Severe Pain. This Medication Decreases The Hormones That Cause Inflammation And Pain In The Body.
Drug Interaction of Diclofenac Sodium :Diclofenac, Like Other NSAIDs Is Associated With Several Suspected Or Probable Interactions That Affect The Action Of Other Drugs. Some Examples Are Discussed Below. Diclofenac May Increase The Blood Levels Of Lithium (Eskalith) By Reducing The Excretion Of Lithium By The Kidneys. Increased Levels Of Lithium May Lead To Lithium Toxicity. Diclofenac May Reduce The Blood Pressure Lowering Effects Of Blood Pressure Medications. This May Occur Because Prostaglandins Play A Role In The Regulation Of Blood Pressure. When Diclofenac Is Used In Combination With Aminoglycoside Antibiotics [for Example, Gentamicin (Garamycin)] The Blood Levels Of The Aminoglycoside May Increase, Presumably Because The Elimination Of Aminoglycosides From The Body Is Reduced. This May Lead To More Aminoglycoside-related Side Effects. Individuals Taking Oral Blood Thinners Or Anticoagulants [for Example,warfarin (Coumadin)] Should Avoid Diclofenac Because Diclofenac Also Thins The Blood, And Excessive Blood Thinning May Lead To Bleeding. Combining NSAIDs With Methotrexate (Rheumatrex, Trexall) May Reduce The Elimination Of Methotrexate From The Body And Result In Increased Side Effects From Methotrexate.
Side effects of Diclofenac Sodium :Nausea, Stomach Upset, Skin Rash, Acute Toxicity.


How Diclofenac Sodium will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Diclofenac Sodium will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Diclofenac Sodium

No Studies Found

Generic ( Camylofine )

Typical use Of Camylofine :Angina, Biliary Colic, Dysmenorrhoea, Migraine, Myocardial Infarction, Pancreatitis.
Mechanism of action of Camylofine :Camylofin Is A Smooth Muscle Relaxant With Both Anticholinergic Action As Well As Direct Smooth Muscle Action. Anticholinergic Action Is Produced By Inhibiting The Binding Of Acetylcholine To Muscarinic Receptors, But The Action Is Less Pronounced. Direct Smooth Muscle Relaxation Is Achieved By Inhibiting Phosphodiesterase Type IV, Which Leads To Increased Cyclic AMP And Eventually Reduced Cytosolic Calcium.
Drug Interaction of Camylofine :Camylofin Is Known To Interact With Other Drugs Like Amantadine, Quinidine And Tricyclic Antidepressants. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Camylofine :Tachycardia, Dry Mouth, Redness, Disturbances Of Accomodation, Glaucoma, Reduced Sweating.


How Camylofine will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Camylofine will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Camylofine

No Studies Found