Medicine : Bcbg

Name:Bcbg
Type:Ointment
Manufacturer:John Walter Labs
Generic Use:Clobetasole Propionate , Miconazole Nitrate , Neomycin
Composition:Clobetasole Propionate(1) , Miconazole Nitrate(1) , Neomycin(1)
Substitutes:bcbg , bcbg , bcbg


Generic ( Clobetasole Propionate )


Typical use Of Clobetasole Propionate :Skin Infection
Mechanism of action of Clobetasole Propionate :The Precise Mechanism Of The Antiinflammatory Activity Of Topical Steroids In The Treatment Of Steroid-responsive Dermatoses, In General, Is Uncertain. However, Corticosteroids Are Thought To Act By The Induction Of Phospholipase A2 Inhibitory Proteins, Collectively Called Lipocortins. It Is Postulated That These Proteins Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes By Inhibiting The Release Of Their Common Precursor Arachidonic Acid. Arachidonic Acid Is Released From Membrane Phospholipids By Phospholipase A2. Initially, However, Clobetasol, Like Other Corticosteroids, Bind To The Glucocorticoid Receptor, Which Complexes, Enteres The Cell Nucleus And Modifies Genetic Transcription (transrepression/transactivation).
Drug Interaction of Clobetasole Propionate :If Overdose Is Suspected, Contact Your Physician.
Side effects of Clobetasole Propionate :Headache, Fatigue, Nausea, Constipation, Dry Mouth, Sedation, Skin Rash, Gastralgia.

INTERACTIONS OF CLOBETASOLE PROPIONATE

How Clobetasole Propionate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clobetasole Propionate will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Clobetasole Propionate

No Studies Found





Generic ( Miconazole Nitrate )


Typical use Of Miconazole Nitrate :Balanitis, Candidosis, Fungal Infection, Vulvo-vaginal Candidosis.
Mechanism of action of Miconazole Nitrate :Miconazole Interacts With 14-? Demethylase, A Cytochrome P-450 Enzyme Necessary To Convert Lanosterol To Ergosterol, Causes Inhibition Of Ergosterol Synthesis Results In Increased Cellular Permeability Causing Leakage Of Cellular Contents. Miconazole May Also Inhibit Endogenous Respiration, Interact With Membrane Phospholipids, Inhibit The Transformation Of Yeasts To Mycelial Forms, Inhibit Purine Uptake, And Impair Triglyceride And/or Phospholipid Biosynthesis.
Drug Interaction of Miconazole Nitrate :Miconazole (Nitrate) Is Known To Interact With Other Drugs Like Alprazolam, Amphotericin B,astemizole, Carbamazepine, Cisapride, Fosphenytoin, Phenytoin (Na). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Miconazole Nitrate :Cardiac Arrhythmias, Phlebitis, Pruritis, Arachnoiditis, Cardiac Arrest, Anaphylaxis, Drowsiness, Anorexia, Rashes, GI Upset, Flushing, Nausea And Vomiting

INTERACTIONS OF MICONAZOLE NITRATE

How Miconazole Nitrate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Miconazole Nitrate will impact during lactation(breastfeeding) ?

Safer: Drug Has Been Studied In Few Breastfeeding Women And The Evidence Shows That There Is No Increase In Side Effects In The Infants, Or The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Miconazole Nitrate

No Studies Found





Generic ( Neomycin )


Typical use Of Neomycin :To Prevent Or Treat Bacterial Diarrhea And Dysentery. It Is Also Used For Pre-operative Sterilization Of The Bowel And To Reduce Symptoms Of Coma Due To Liver Disease (hepatic Coma); To Cure Infected Wound, Ulcers, Burn, External Ear Infections And Conjunctivitis.
Mechanism of action of Neomycin :Neomycin Prevents The Bacterial Growth By Inhibiting The Synthesis Of Protein In Susceptible Bacterial Cells.
Drug Interaction of Neomycin :Neomycin May Interact With Drugs Including Phenoxymethyl Penicillin, Digoxin, Methotrexate, Acarbose, Atracurium, Cyanocobalamin, Doxacurium, Fluorouracil, Gentamicin, Gestodene And Pancuronium Bromide, Neostigmine And Pyridostigmine. Caution Should Be Taken On The Use Of Neomycin With Drugs Known To Cause Kidney Related Problems, Including Aminoglycosides, Cephalosporins, Amphotericin, Ciclosporin, Capreomycin, Polymixins, Platinum Compounds, Teicoplanin And Vancomycin) And Ototoxicity (including Loop Diuretics, Capreomycin, Teicoplanin, Vancomycin And Possibly Platinum Compounds). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Neomycin :Urge To Vomit (nausea), Vomiting, Diarrhea, Increased Salivation, Stomatitis, Nephrotoxicity, Ototoxicity (hearing Problem), Rise In Serum Levels Of Liver Enzymes And Bilirubin, Imbalance Of Blood Components (blood Dyscrasias), Low Hemoglobin Or Red Blood Cells (hemolytic Anemia), Confusion, Tingling Or Burning Sensation (paresthesia), Disorientation, Rapid Movement Of The Eyeballs (nystagmus), Hypersensitivity Reactions Including Dermatitis, Itching (pruritus), Drug Fever And Anaphylaxis.

INTERACTIONS OF NEOMYCIN

How Neomycin will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Neomycin will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Neomycin

No Studies Found