Medicine : Azinet (300)

Name:Azinet (300)
Type:Injection
Manufacturer:Laxian Incorporation
Generic Use:Netilmicin
Composition:Netilmicin(300 Mg)
Substitutes:netgen (300mg) , netcin (300mg) , netsun (300mg) , netilmac (300mg) , azinet (300)


Generic ( Netilmicin )



Typical use Of Netilmicin :Infection Mainly Caused By Gram-negative Micro-organisms Usually Resistant To Kanamycin, Gentamicin, Tobramycin, Sisomicin And Amikacin.
Mechanism of action of Netilmicin :Netilmicin Irreversibly Bind To Specific 30S-subunit Proteins And 16S RRNA. Specifically Netilmicin Binds To Four Nucleotides Of 16S RRNA And A Single Amino Acid Of Protein S12. This Interferes With Decoding Site In The Vicinity Of Nucleotide 1400 In 16S RRNA Of 30S Subunit. This Region Interacts With The Wobble Base In The Anticodon Of TRNA. This Leads To Interference With The Initiation Complex, Misreading Of MRNA So Incorrect, Amino Acids Are Inserted Into The Polypeptide Leading To Nonfunctional Or Toxic Peptides And The Breakup Of Polysomes Into Nonfunctional Monosomes, Leaving The Bacterium Unable To Synthesize Proteins Vital To Its Growth.
Drug Interaction of Netilmicin :Netilmicin (Sulphate) Is Known To Interact With Other Drugs Like Cephradine, Cisplatin, Gentamicin, Polymyxin B (Sulphate), Vancomycin (HCl). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Netilmicin :Nephrotoxicity, Ototoxicity, Nausea, Vomiting, Maculopapular Rash, Urticaria, Pain, Phlebitis, Elevated Hepatic Transaminases.

INTERACTIONS OF NETILMICIN


How Netilmicin will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Netilmicin will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Netilmicin

No Studies Found