Medicine : Apruv Lt Tab

Name:Apruv Lt Tab
Type:Tablet
Manufacturer:Emcure Pharmaceuticals Ltd
Generic Use:Amlodipine , Losartan
Composition:Amlodipine(2.5mg) , Losartan(50mg)
Substitutes:eslo tan tab , espin lt , espinlt , eslo tan , apruv lt tab , eslo tan tab , espin lt , espinlt , eslo tan , apruv lt tab


Generic ( Amlodipine )



Typical use Of Amlodipine :Amlodipine Is Used To Treat High Blood Pressure And Various Forms Of Angina (severe Pain In Chest Which May Travel Into The Jaw, Neck And Arms Or Narrowing Of The Coronary Arteries Of The Heart.
Mechanism of action of Amlodipine :Amlodipine Is An Anti-hypertensive Drug That Relaxes And Opens Blood Vessels, Thus, Improving The Flow Of Blood And Lowering The Blood Pressure. It Improves Blood And Oxygen Supply To The Heart Muscles.
Drug Interaction of Amlodipine :Grapefruit Juice May Increase Plasma Concentration Of Amlodipine. Amlodipine May Cause Excessive Reduction In Blood Pressure On Interaction With Calcium, Sildenafil, Tadalafil Or Vardenafil. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Amlodipine :The Common Side Effects Are Headache, Swelling Of Part Or Whole Of Body, Rash, Unusual Tiredness, Urge To Vomit, Facial Redness And Feeling Of Warmth (flushing), Sleepiness, Dizziness, Headache, Swelling Of Ankle, Face, Lips And Eyes, Sleepiness, Abdominal Pain, Indigestion, Drowsiness, And Thumping, Pounding Or Fluttering Sensation In The Chest

INTERACTIONS OF AMLODIPINE


How Amlodipine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Amlodipine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Amlodipine

No Studies Found






Generic ( Losartan )



Typical use Of Losartan :Mild To Moderate Hypertension.Diabetic Nephropathy In Type 2 Diabetes Mellitus.
Mechanism of action of Losartan :Losartan Is An Angiotensin II Receptor Antagonist. The Drug And Its Active Metabolite Selectively Block The Vasoconstrictor And Aldosterone-secreting Effects Of Angiotensin II By Selectively Antagonising Its Binding To AT1 Receptors.
Drug Interaction of Losartan :Losartan May Increase Levels Of Blood Potassium (hyperkalemia), Which Can Lead To Serious Heart Problems (arrhythmias). Therefore, Concomitant Use Of Other Drugs Or Substances That Increase Blood-such As Potassium-sparing Diuretics (for Example, Spironolactone[Aldactone], Triamterene, And Amiloride), Potassium Supplements, Or Salt Substitutes Containing Potassium May Lead To Dangerous Increases In Serum Potassium. Combining Losartan Or Other ARBs With Nonsteroidal Anti-inflammatory Drugs(NSAIDs) In Patients Who Are Elderly, Fluid-depleted (including Those On Diuretic Therapy), Or With Poor Kidney Function May Result In Reduced Kidney Function, Including Kidney Failure. These Effects Usually Are Reversible. The Antihypertensive Effect Of Losartan May Be Reduced By Aspirin And Other NSAIDs Such As Ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, Etc.), Indomethacin (Indocin, Indocin-SR), And Naproxen (Anaprox, Naprelan, Naprosyn, Aleve).
Side effects of Losartan :Headache, Dizziness, Back Pain, Myalgia, Respiratory Tract Disorders, Fatigue, GI Disturbances, Transient Elevation Of Liver Enzymes, Impaired Renal Function, Taste Disturbances And Hyperkalaemia.

INTERACTIONS OF LOSARTAN


How Losartan will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Losartan will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Losartan

No Studies Found