Medicine : Amlopres At(25tab)

Name:Amlopres At(25tab)
Manufacturer:Cipla Ltd
Generic Use:Atenolol , Amlodipine Besylate
Composition:Atenolol(25 Mg) , Amlodipine Besylate(5mg)
Substitutes:atpure sa tab , amlopres at(25tab) , atpure sa tab , amlopres at(25tab)

Generic ( Atenolol )

Typical use Of Atenolol :To Control High Blood Pressure, Prevent Chest Pain, Control Heart Rhythm Disorders And Prevention Of Severe Headache (migraine).
Mechanism of action of Atenolol :Atenolol Blocks Beta Receptors (beta Blockers) In The Heart And Peripheral Blood Vessels Resulting In Slowing Of Heart Rate And Relaxing Of Blood Vessels Thereby Lowering Blood Pressure. Atenolol Reduces Oxygen Requirement At Any Level Of Activity Making It Useful For Long-term Management Of Heart Attacks Caused By Restricted Cardiac Blood Flow.
Drug Interaction of Atenolol :NSAIDs Such As Ibuprofen, Naproxen And Calcium Channel Blockers (verapamil, Nifedipine And Diltiazem) Taken With Atenolol Can Severely Lower Blood Pressure And Reduce Heart Rate. Atenolol When Administered With Antiarrhythmic Drugs (disopyramide, Amiodarone), Digoxin Can Cause Severe Lowering Of Heart Rate. Use Of Other Hypotensive With Atenolol Can Cause Excess Lowering Of Blood Pressure. Both Digitalis Glycosides And Beta-blockers Slow Atrioventricular Conduction And Decrease Heart Rate. Concomitant Use Can Decrease The Heart Rate (bradycardia). Administration With Insulin Or Other Oral Anti-diabetics Can Impair Sugar Control. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Atenolol :Narrowing Of Airways, Wheezing, Slowing Of Heart Rate, Low Blood Pressure, Heart Failure, Heart Block, Cold Hands And Feet, Feeling Tired And Weak, Dizziness, Confusion, Drowsiness, Feeling Depressed, Urge To Vomit (nausea), Diarrhea, Constipation, And Inability To Maintain Erection (sexual Dysfunction).


How Atenolol will impact on Pregnancy ?

Experiences Of Drug Use And Evidence From Studies In Pregnant Women Have Shown Risk To Fetus. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Atenolol will impact during lactation(breastfeeding) ?

Possibly Unsafe: Evidence From Studies In Breastfeeding Women Show That There Is A Definite Risk Of Side Effects To The Breastfed Infants. However, Use Of The Drug In Breastfeeding Women Is Acceptable In Spite Of The Risk To The Infants, If The Drug Is Needed In A Life-threatening Situation Or For A Serious Disease For Which Safer Drugs Cannot Be Used Or Are Ineffective. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Atenolol

No Studies Found

Generic ( Amlodipine Besylate )

Typical use Of Amlodipine Besylate :Mild To Moderate Hypertension.Angina Pectoris.Prinzmetals Angina.
Mechanism of action of Amlodipine Besylate :Amlodipine Relaxes Peripheral And Coronary Vascular Smooth Muscle. It Produces Coronary Vasodilation By Inhibiting The Entry Of Ca Ions Into The Voltage-sensitive Channels Of The Vascular Smooth Muscle And Myocardium During Depolarisation. It Also Increases Myocardial O2 Delivery In Patients With Vasospastic Angina.
Drug Interaction of Amlodipine Besylate :Increased Metabolism With Rifampin. Reduced Hypotensive Effect With Calcium. Potentiates Effects Of Thiazide Diuretics And ACE Inhibitors. Avoid Combination With ?-blockers In Patients With Markedly Impaired Left Ventricular Function. May Increase Serum Levels Of CYP1A2 Substrates E.g. Aminophylline, Fluvoxamine, Ropinirole. CYP3A4 Inhibitors (e.g. Clarithromycin, Doxycycline, Isoniazid, Nicardipine) May Increase The Effects Of Amlodipine. Additive BP-lowering Effects When Used With Sildenafil, Tadalafil Or Vardenafil.
Side effects of Amlodipine Besylate :Headache, Peripheral Oedema, Fatigue, Somnolence, Nausea, Abdominal Pain, Flushing, Dyspepsia, Palpitations, Dizziness. Rarely Pruritus, Rash, Dyspnoea, Asthenia, Muscle Cramps. Potentially Fatal: Hypotension, Bradycardia, Conductive System Delay And CCF.


How Amlodipine Besylate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Amlodipine Besylate will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Amlodipine Besylate

No Studies Found