Medicine : Adelphane Esidrex Tab

Name:Adelphane Esidrex Tab
Type:Tablet
Manufacturer:Novartis Pharmaceuticals Ltd
Generic Use:Dihydralazine Sulphate , Hydrochlorothiazide , Reserpine
Composition:Dihydralazine Sulphate() , Hydrochlorothiazide(10 Mg) , Reserpine(0.1 Mg)
Substitutes:adelphane esidrex tab , adelphane esidrex tab , adelphane esidrex tab


Generic ( Dihydralazine Sulphate )



Typical use Of Dihydralazine Sulphate :Hypertension.
Mechanism of action of Dihydralazine Sulphate :Dihydralazine Is A Direct-acting Vasodilator Which Acts Predominantly On The Arterioles. It Reduces BP And Peripheral Resistance Thus Increasing Cardiac Output. It Also Tends To Improve Renal And Cerebral Blood Flow And Its Effect On Diastolic Pressure Is More Marked Than On Systolic Pressure.
Drug Interaction of Dihydralazine Sulphate :Dihydralazine Sulphate Is Known To Interact With Other Drugs Like Diazoxide, Thiazide Diuretics. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Dihydralazine Sulphate :Tachycardia, Palpitations, Angina Pectoris, Severe Headache, GI Disturbances, Flushing, Dizziness, Nasal Congestion, Postural Hypotension, Fluid Retention With Oedema And Wt Gain, Conjunctivitis, Lachrymation, Tremor, Peripheral Neuropathy With Numbness And Tingling Of Extremities, Muscle Cramps, Hepatotoxicity, Blood Dyscrasias.

INTERACTIONS OF DIHYDRALAZINE SULPHATE


How Dihydralazine Sulphate will impact on Pregnancy ?

There Are No Studies Available Regarding Its Use During Pregnancy. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Dihydralazine Sulphate will impact during lactation(breastfeeding) ?

There Are No Studies Available Regarding Its Use During Lactation. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Dihydralazine Sulphate

No Studies Found






Generic ( Hydrochlorothiazide )



Typical use Of Hydrochlorothiazide :Hydrochlorothiazide Is Used For The Treatment Of High Blood Pressure And Swelling Of The Body Due To Heart, Liver Or Renal Diseases And Corticosteroid Or Estrogen Therapy.
Mechanism of action of Hydrochlorothiazide :Hydrochlorothiazide Belongs To The Group Of Medicines Called Diuretics Which Increase The Urine Output. It Decreases Blood Pressure Together With Other Drugs (angiotensin Convertase Enzyme Inhibitors) That Reduce The Levels Of A Substance Called Angiotensin II.
Drug Interaction of Hydrochlorothiazide :Hydrochlorothiazide May Interact With Other Drugs Including Aspirin, Ibuprofen, Tubocurarine, Lithium Containing Drugs, Digitalis Glycosides, Nitrates Or Vasodilators, Cholestyramine,colestipol, Alcohol, Narcotics, And Corticosteroids. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Hydrochlorothiazide :Dizziness , Headache, Tiredness, Weakness, Sleepiness Or Sleeplessness, Diarrhea, Indigestion, Mild Stomach Pain, Urge To Vomit, Vomiting, Painful Muscles, Muscle Weakness, Back Pain, High Levels Of Uric Acid In The Blood Causing Swollen And Painful Joints, Nose Or Throat Infections, Nasal Stuffiness And/or Runny Nose.

INTERACTIONS OF HYDROCHLOROTHIAZIDE


How Hydrochlorothiazide will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Hydrochlorothiazide will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Hydrochlorothiazide

No Studies Found






Generic ( Reserpine )



Typical use Of Reserpine :Hypertension.
Mechanism of action of Reserpine :Reserpine Is An Antihypertensive Drug That Causes Depletion Of Noradrenaline, Catecholamine And Serotonin Stores Resulting In A Reduction In BP, Bradycardia And CNS Depression. Decrease In Cardiac Output And Peripheral Resistance Result In Hypotensive Effect.
Drug Interaction of Reserpine :Hypotensive Effects Enhanced By Thiazide Diuretics And Other Antihypertensives.
Side effects of Reserpine :Drowsiness, Dyspepsia, Weight Gain, Nightmares, Galactorrhea, Menstrual Irregularity, Amenorrhea, Disturbed Sleep, Nasal Obstruction, Looseness Of Bowel.

INTERACTIONS OF RESERPINE


How Reserpine will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Reserpine will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Reserpine

No Studies Found