Medicine : Acuclav 250/(125mg)

Name:Acuclav 250/(125mg)
Type:Tablet
Manufacturer:Macleods Pharmaceuticals Ltd
Generic Use:Amoxicillin , Potassium Clavulanate , Clavulanic Acid
Composition:Amoxicillin(250 Mg) , Potassium Clavulanate(125 Mg) , Amoxicillin(500mg) , Clavulanic Acid(125mg)
Substitutes:acuclav 250/(125mg) , acuclav 250/(125mg) , acuclav 250/(125mg) , acuclav 250/(125mg)


Generic ( Amoxicillin )



Typical use Of Amoxicillin :Amoxicillin Is Used To Treat Bacterial Infections Of The Respiratory Tract, Genital And Urinary Tract, Skin And Soft Tissue, Ear, Nose And Throat, Heart, Blood, Teeth, And Gums.
Mechanism of action of Amoxicillin :Amoxicillin Kills Bacteria By Interfering With The Production Of The Bacterial Cell Wall. As A Result, The Bacterial Cell Wall Is Weakened, The Cell Swells And Then Ruptures.
Drug Interaction of Amoxicillin :Warfarin, Probenecid, Allopurinol, And Methotrexate Are Known To Cause Increased Blood Level Of Amoxicillin. Amoxicillin Decreases The Effects Of Chloramphenicol And Oral Contraceptives. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Amoxicillin :The Common Side Effects Are Diarrhea, Urge To Vomit, And Vomiting, Skin Rash. You May Also Experience Diarrhea, Stomach Upset, Seizures, Decrease In White Blood Cells, Prolonged Bleeding Time, Swelling, Hypersensitivity, Stomach Pain Or Severe Diarrhea (possibly With Bleeding), Yellow Eyes Or Skin, Flu, Loss Of Appetite, Unusual Bleeding Of Skin Or Bruising Or Skin Discoloration, Rashes And Itching, Blistering Of The Skin, Mouth, Eyes, Or Genitals, Wheezing, Difficulty In Breathing, Feeling Dizzy, Swelling Of Face, Neck Or Tongue, Pain Or Burning While Urinating With Darker Urine.

INTERACTIONS OF AMOXICILLIN


How Amoxicillin will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Amoxicillin will impact during lactation(breastfeeding) ?

Safest: Evidence From Clinical Studies Has Shown That This Drug When Taken By Breastfeeding Mothers Has Not Shown Any Major Side Effects In Infants. The Possibility Of Harm To The Breastfed Infants Is Expected To Be Rare Or The Drug Does Not Reach The Infant Through Breast Milk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Amoxicillin

No Studies Found






Generic ( Potassium Clavulanate )



Typical use Of Potassium Clavulanate :Bacterial Infections, Myeloablative Therapy Followed By Bone Marrow Transplantation, Respiratory Tract Infections, Urinary Tract Infection.
Mechanism of action of Potassium Clavulanate :Clavulanic Acid Competitively And Irreversibly Inhibits A Wide Variety Of Beta-lactamases, Commonly Found In Microorganisms Resistant To Penicillins And Cephalosporins. Binding And Irreversibly Inhibiting The Beta-lactamase Results In A Restauration Of The Antimicrobial Activity Of Beta-lactam Antibiotics Against Lactamase-secreting-resistant Bacteria. By Inactivating Beta-lactamase (the Bacterial Resistance Protein), The Accompanying Penicillin/cephalosporin Drugs May Be Made More Potent As Well.
Drug Interaction of Potassium Clavulanate :Allopurinol May Reduce Renal Tubular Secretion Of Amoxicillin Thus Increasing The Serum Levels Of Amoxicillin. Concurrent Use May Reduce The Efficacy Of Oral Contraceptives.
Side effects of Potassium Clavulanate :Diarrhea, Fever, Maculopapular Rash, Urticaria, Increase In Serum Transaminase.

INTERACTIONS OF POTASSIUM CLAVULANATE


How Potassium Clavulanate will impact on Pregnancy ?

Studies In Animals Have Shown Risk To Fetus, However There Are No Sufficient Studies In Humans. This Drug May Be Used In Pregnant Women If Benefit Outweighs The Risk. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Potassium Clavulanate will impact during lactation(breastfeeding) ?

Contraindicated: The Drug Should Not Be Used By Breastfeeding Women, As Evidences From Studies Have Shown That There Is A High Risk Of Causing Significant Damage To Infants.

Medicine & Alcohol use and effect of Potassium Clavulanate

No Studies Found






Generic ( Clavulanic Acid )



Typical use Of Clavulanic Acid :Clavulanic Acid Is Used To Increase The Effect Of Certain Antibiotics (amoxicillin) To Treat Bacterial Infections Of The Respiratory Tract, Urinary Tract, Ear, Nose And Throat, Skin And Soft Tissues, Bone And Joints, And To Prevent Infections After Surgery. It Is Never Used Alone To Treat Infections.
Mechanism of action of Clavulanic Acid :Clavulanic Acid Blocks The Activity Of A Chemical (beta-lactamase), Which Is Secreted By Bacteria To Protect Themselves From Antibiotic Drugs Like Amoxicillin, Thereby Allowing The Antibiotics To Act Against The Bacteria.
Drug Interaction of Clavulanic Acid :Clavulanic Acid Is Known To Interact With Other Drugs Like Methotrexate, Probenicid, Ethinyl Estradiol, Aminoglycosides (gentamycin, Streptomycin, And Neomycin). Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Clavulanic Acid :When Used In Combination With Antibiotics Like Amoxicillin, The Common Side Effects Are Diarrhea, Inflammation Of The Large Intestine, Causing Diarrhea With Blood And Mucus In Stools, Stomach Pain, Fever, Thrush (fungal Infection Of The Vagina, Mouth And Skin Folds), Urge To Vomit, Vomiting, Hypersensitivity Reactions Like Fever, Skin Rash And Hives (red, Itchy Bumps On Skin), Liver Dysfunction And Toxicity, And Jaundice.

INTERACTIONS OF CLAVULANIC ACID


How Clavulanic Acid will impact on Pregnancy ?

Studies In Animals Have Shown No Risk To The Fetus, However There Are No Sufficient Studies In Humans. Patients Should Follow The Advice Of The Doctor Regarding Its Use. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

How Clavulanic Acid will impact during lactation(breastfeeding) ?

Moderately Safe: No Studies Have Been Conducted In Breastfeeding Women, However There Is Possibility Of Ill Effect To The Breastfed Infants; Or Studies Conducted In Breastfeeding Women Show Minimal Non-threatening Side Effects To The Infants. Drugs Should Be Given Only If The Potential Benefit Justifies The Potential Risk To The Infant. Patients Should Follow The Advice Of The Doctor Regarding Its Use.

Medicine & Alcohol use and effect of Clavulanic Acid

No Studies Found