Medicine : Insuman (40iu)

Name:Insuman (40iu)
Manufacturer:Sanofi India Ltd (aventis)
Generic Use:Insulin Isophane
Composition:Insulin Isophane(40 IU)

Generic ( Insulin Isophane )

Typical use Of Insulin Isophane :Diabetes Mellitus.
Mechanism of action of Insulin Isophane :Insulin Isophane Binds To The Insulin Receptor (IR), A Heterotetrameric Protein Consisting Of Two Extracellular Alpha Units And Two Transmembrane Beta Units. The Binding Of Insulin To The Alpha Subunit Of IR Stimulates The Tyrosine Kinase Activity Intrinsic To The Beta Subunit Of The Receptor. The Bound Receptor Is Able To Autophosphorylate And Phosphorylate Numerous Intracellular Substrates Such As Insulin Receptor Substrates (IRS) Proteins, Cbl, APS, Shc And Gab 1. These Activated Proteins, In Turn, Lead To The Activation Of Downstream Signaling Molecules Including PI3 Kinase And Akt. Akt Regulates The Activity Of Glucose Transporter 4 (GLUT4) And Protein Kinase C (PKC) Which Play A Critical Role In Metabolism And Catabolism.
Drug Interaction of Insulin Isophane :Insulin Isophane Is Known To Interact With Other Drugs Like MAOIs, ACE Inhibitors, Salicylates, Alcohol, Anabolic Steroids And Non-selective β-blockers. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Insulin Isophane :Injection Site Reactions E.g. Swelling, Redness, Itch And Pain.


How Insulin Isophane will impact on Pregnancy ?

Information Not Available.

How Insulin Isophane will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Insulin Isophane

Information Not Available.