Medicine : Genticyn Pead(10mg)

Name:Genticyn Pead(10mg)
Manufacturer:Abbott India Ltd
Generic Use:Gentamicin Sulfate
Composition:Gentamicin Sulfate(10 Mg)

Generic ( Gentamicin Sulfate )

Typical use Of Gentamicin Sulfate : Acute Diarrhoea, Bacterial Infections, Biliary Tract Infections, Endocarditis, Food Allergy, Muscle Relaxation (intermediate Duration) During Intensive Care, Muscle Relaxation (intermediate Duration) For Surgery Or Intubation, Muscle Relaxation (long Duration) During Intensive Care, Pneumonia In Hospital Patients, Septicaemia, Ulcerative Colitis.
Mechanism of action of Gentamicin Sulfate :Aminoglycosides Like Gentamicin "irreversibly" Bind To Specific 30S-subunit Proteins And 16S RRNA. Specifically Gentamicin Binds To Four Nucleotides Of 16S RRNA And A Single Amino Acid Of Protein S12. This Interferes With Decoding Site In The Vicinity Of Nucleotide 1400 In 16S RRNA Of 30S Subunit. This Region Interacts With The Wobble Base In The Anticodon Of TRNA. This Leads To Interference With The Initiation Complex, Misreading Of MRNA So Incorrect Amino Acids Are Inserted Into The Polypeptide Leading To Nonfunctional Or Toxic Peptides And The Breakup Of Polysomes Into Nonfunctional Monosomes.
Drug Interaction of Gentamicin Sulfate :Gentamicin Is Known To Interact With Other Drugs Like Atracurium (Besylate), Capreomycin, Cefaclor (Monohydrate), Cefotaxime, Cisplatin, Clindamycin, Cyclosporin A, Cytarabine (HCl), Ethacrynic Acid, Ethacrynic Acid, Floxacillin (Na), Foscarnet (Na), Frusemide Or Furosemide, Hydrocortisone, Indomethacin.
Side effects of Gentamicin Sulfate :Encephalopathy, Convulsions, Hallucinations, Nephrotoxicity, Neuromuscular Blockage, Nephrotoxicity, Ototoxicity, Dizziness, Vertigo, Fever, Ototoxicity, Skin Rashes, Exfoliative Dermatitis, Eosinophilia, Purpura, Angioedema, Pyuria, Proteinuria, Azotemia.


How Gentamicin Sulfate will impact on Pregnancy ?

Information Not Available.

How Gentamicin Sulfate will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Gentamicin Sulfate

Information Not Available.