Medicine : Clop G Cream(125g)

Name:Clop G Cream(125g)
Manufacturer:Liva Healthcare Ltd
Generic Use:Clobetasol , Gentamicin
Composition:Clobetasol(0.05%) , Gentamicin(0.10%)

Generic ( Clobetasol )

Typical use Of Clobetasol :To Treat Itching, Redness, Dryness, Inflammation, And Discomfort Of Various Scalp And Skin Conditions, Including Psoriasis (immune-mediated Skin Disease With Red Scaly Patches) And Eczematous Dermatitis.
Mechanism of action of Clobetasol :Clobetasol Is A Highly Active Corticosteroid With Topical Anti-inflammatory Activity. It Reduces Inflammation By Vasoconstriction And Decrease In Collagen Synthesis. When Clobetasol Is Applied To The Skin It Works By Acting Inside The Skin Cells To Decrease The Release Of These Inflammatory Substances. This Reduces Swelling, Redness And Itch.
Drug Interaction of Clobetasol :Clobestol May Interact With Prednisone And Cyclosporine. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Clobetasol :Severe Irritation Of Treated Skin, Soreness Around The Mouth, Burning, Dryness, Irritation, Itching, Or Redness Of Skin (usually Mild And Temporary), Eye Pain (if Certain Products Have Been Used Near The Eye), Headache, Increased Redness Or Scaling Of Skin Sores (usually Mild And Temporary), Changes In Skin Color, Skin Infection, Skin Rash (usually Mild And Temporary), Softening And Tearing Of The Skin And Thinning Of The Skin With Easy Bruising.


How Clobetasol will impact on Pregnancy ?

Information Not Available.

How Clobetasol will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Clobetasol

Information Not Available.

Generic ( Gentamicin )

Typical use Of Gentamicin :Severe Infections Caused By Susceptible Gm Negative Organisms Eg - Billary Tract Infections, Brucellosis, Cat Scratch Disease, Cystic Fibrosis, Endocarditis, Endometritis, Gastroenteritis, Granuloma Inguinale, Listeriosis, Meningitis, Otitis Externa, Pelvic Inflammatory Disease, Peritonitis, Plaque, Pneumonia, Septicaemia, Skin Infections, UTI.
Mechanism of action of Gentamicin :Aminoglycosides Like Gentamicin "irreversibly" Bind To Specific 30S-subunit Proteins And 16S RRNA. Specifically Gentamicin Binds To Four Nucleotides Of 16S RRNA And A Single Amino Acid Of Protein S12. This Interferes With Decoding Site In The Vicinity Of Nucleotide 1400 In 16S RRNA Of 30S Subunit. This Region Interacts With The Wobble Base In The Anticodon Of TRNA. This Leads To Interference With The Initiation Complex, Misreading Of MRNA So Incorrect Amino Acids Are Inserted Into The Polypeptide Leading To Nonfunctional Or Toxic Peptides And The Breakup Of Polysomes Into Nonfunctional Monosomes.
Drug Interaction of Gentamicin :Gentamicin Is Known To Interact With Other Drugs Like Atracurium (Besylate), Capreomycin, Cefaclor (Monohydrate), Cefotaxime, Cisplatin, Clindamycin, Cyclosporin A, Cytarabine (HCl), Ethacrynic Acid, Ethacrynic Acid, Floxacillin (Na), Foscarnet (Na), Frusemide Or Furosemide, Hydrocortisone, Indomethacin.
Side effects of Gentamicin :Encephalopathy, Convulsions, Hallucinations, Nephrotoxicity, Neuromuscular Blockage, Nephrotoxicity, Ototoxicity, Dizziness, Vertigo, Fever, Ototoxicity, Skin Rashes, Exfoliative Dermatitis, Eosinophilia, Purpura, Angioedema, Pyuria, Proteinuria, Azotemia.


How Gentamicin will impact on Pregnancy ?

Information Not Available.

How Gentamicin will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Gentamicin

Information Not Available.